Is Your Mouthwash Raising Your Blood Pressure? What You Need to Know

May 22, 2025 | Blog

If you’re like most people, using mouthwash is just another step in your daily hygiene routine. Swish. Spit. Done. It promises fresher breath, fewer germs, and a cleaner mouth. But here’s something that might surprise you. Some mouthwashes may actually be doing more harm than good, especially when it comes to your blood pressure.

Let’s take a closer look at what’s really going on behind that minty swish.

Why Mouthwash Was Made in the First Place

We all want that just-left-the-dentist clean feeling. That’s why mouthwash has become a staple in so many bathrooms. It’s convenient, easy to use, and the promise of killing 99.9 percent of germs is hard to resist. Antiseptic mouthwashes, especially those with ingredients like chlorhexidine and cetylpyridinium chloride, are designed to wipe out harmful bacteria.

But not all bacteria in your mouth are bad. In fact, some of them play a crucial role in keeping your whole body healthy.

Meet the Bacteria That Help Regulate Your Blood Pressure

Your mouth is home to millions of bacteria. While some contribute to plaque and gum disease, others have a more surprising role. They help your body produce nitric oxide, which is essential for relaxing blood vessels and keeping your blood pressure in check.

Here’s how it works. When you eat nitrate-rich foods like spinach, arugula, or beets, your body relies on oral bacteria to convert those nitrates into nitrites. Once swallowed, those nitrites are further transformed into nitric oxide. Without those helpful mouth bacteria, that chain reaction breaks down.

So what happens when mouthwash kills off the good bacteria?

The Scientific Link Between Mouthwash and High Blood Pressure

Researchers have started to notice a pattern. People who use antiseptic mouthwash twice a day or more may have a higher risk of developing high blood pressure.

One key study, the San Juan Overweight Adults Longitudinal Study, found that those who used mouthwash more than once a day were significantly more likely to develop hypertension. Other clinical trials have shown that even short-term use of certain antibacterial mouthwashes can raise systolic blood pressure in healthy people.

The reason is simple. These mouthwashes disrupt the nitrate to nitrite to nitric oxide pathway by killing off the bacteria that help produce nitric oxide. Less nitric oxide means less blood vessel relaxation, which can lead to higher blood pressure.

Not All Mouthwashes Are Created Equal

It’s important to know that not every mouthwash poses the same risk. The type you use, how often you use it, and your overall health all play a role.

Alcohol-based and chlorhexidine mouthwashes are the most likely to interfere with nitric oxide production.
Natural or alcohol-free options may be gentler on the beneficial bacteria in your mouth.
Hydrogen peroxide rinses and salt water gargles can offer antimicrobial benefits without the same impact on your nitric oxide levels.

If you are using mouthwash daily based on a dentist’s recommendation, such as for gum disease treatment, talk to your provider about safer long-term options.

What Should You Do Instead?

You do not have to stop using mouthwash entirely. But it may be time to rethink how and why you use it.

Focus on Brushing and Flossing First

Brushing and flossing daily are still the gold standard. They physically remove plaque and food particles, which is far more effective than simply rinsing with chemicals.

Use Mouthwash Sparingly

If fresh breath is your main goal, consider using mouthwash once a day or only a few times a week. Look for alcohol-free, fluoride-based, or essential-oil mouthwashes that are less likely to disrupt your oral microbiome.

Eat More Nitrate-Rich Vegetables

Leafy greens, beets, and other nitrate-rich vegetables support nitric oxide production, especially when your oral bacteria are healthy. Your heart and blood vessels will thank you.

Avoid Using Mouthwash Around Exercise Time

Some studies suggest that mouthwash can dull the blood pressure-lowering effects of physical activity. For best results, avoid rinsing within an hour before or after your workout.

What About Bad Breath?

If you are using mouthwash mainly to fight bad breath, it is worth finding out what is really causing it. Chronic bad breath can be a sign of other issues such as gum disease, dry mouth, acid reflux, dietary habits, or even gut imbalances.

At Elite Dental Studio, we take a deeper look using salivary testing and high-magnification microscopy. These tools help us assess your oral microbiome and create a personalized treatment plan. We can determine whether your bad breath is from an imbalance in oral bacteria, a systemic concern, or something else entirely.

Looking Beyond the Surface

It is easy to think of your mouth as separate from the rest of your body. But research continues to show that your oral health and overall health are deeply connected. What you do to your mouth, whether brushing, flossing, or rinsing, can affect your blood vessels, your gut, and even your immune system.

The key is balance. Your mouth is not a battleground. It is an ecosystem. And just like your gut, your oral microbiome thrives when treated with care and thoughtfulness.

Something to Think About

Mouthwash is not automatically harmful. But using it too often or choosing the wrong kind may do more harm than good, especially if you are already managing high blood pressure. If you are using mouthwash every day, now might be the perfect time to reassess your routine.

If you want to know more about how your oral care routine could be impacting your heart, gut, or immune system, we are here to help. At Elite Dental Studio, we believe in whole-body wellness that starts with your mouth.

Want help picking a safer mouthwash or curious about salivary testing? Reach out to us. We would love to guide you toward healthier habits and personalized solutions.